Northern Territory Police are seeking public assistance in locating a youth who has been reported as missing in Alice Springs overnight.

A 12 year old female, was last seen by family members at a residential address in Sadadeen around 6pm yesterday.

The youth was reported as missing after she failed to return home, and was not able to be located by family, who searched the area and known locations, yesterday.

Police and family hold concerns for the youth’s welfare, as she suffered from an underlying medical condition which requires daily medication.

The missing youth is described as being 165cms tall, with a slight built, fair complexion, blonde hair and brown eyes and was last seen wearing a camo-coloured green top and turn-denim shorts.

Police urge anyone who has information as to the missing youths' hereabouts, to contact police immediately o 131 444 or anonymously via crime stoppers on 1800 333 000.

Police urge anyone with information which may assist with investigations, to report it via 131 444 or anonymously via Crime Stoppers on 1800 333 000.